Effects of Apolipoprotein E polymorphism on carotid intima-media thickness, incident myocardial infarction and incident stroke

Abstract The Apolipoprotein E (APOE) gene polymorphism (rs429358 and rs7412) shows a well-established association with lipid profiles, but its effect on cardiovascular disease is still conflicting. Therefore, we examined the association of different APOE alleles with common carotid artery intima-med...

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Bibliographic Details
Main Authors: Anitha Pitchika, Marcello Ricardo Paulista Markus, Sabine Schipf, Alexander Teumer, Sandra Van der Auwera, Matthias Nauck, Marcus Dörr, Stephan Felix, Hans-Jörgen Grabe, Henry Völzke, Till Ittermann
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09129-5