Cystatin C Expression is Promoted by VEGFA Blocking, With Inhibitory Effects on Endothelial Cell Angiogenic Functions Including Proliferation, Migration, and Chorioallantoic Membrane Angiogenesis

Background Vascular development, including vasculogenesis and angiogenesis, is involved in many diseases. Cystatin C (CST3) is a commonly used marker of renal dysfunction, and we have previously reported that its expression level is associated with variations in the gerbil circle of Willis. Thus, we...

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Main Authors: Zhenkun Li, Shiyuan Wang, Xueyun Huo, Hefen Yu, Jing Lu, Shuangyue Zhang, Xiaohong Li, Qi Cao, Changlong Li, Meng Guo, Jianyi Lv, Xiaoyan Du, Zhenwen Chen
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.118.009167