Analyses of Gnai3-iresGFP reporter mice reveal unknown Gαi3 expression sites

Abstract Inhibitory G proteins (Gi proteins) are highly homologous but play distinct biological roles. However, their isoform-specific detection remains challenging. To facilitate the analysis of Gαi3 expression, we generated a Gnai3- iresGFP reporter mouse line. An internal ribosomal entry site...

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Bibliographic Details
Main Authors: Veronika Leiss, Ellen Reisinger, Annika Speidel, Sandra Beer-Hammer, Bernd Nürnberg
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93591-0