miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity.

miR-132 and miR-212 are two closely related miRNAs encoded in the same intron of a small non-coding gene, which have been suggested to play roles in both immune and neuronal function. We describe here the generation and initial characterisation of a miR-132/212 double knockout mouse. These mice were...

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Bibliographic Details
Main Authors: Judit Remenyi, Mirjam W M van den Bosch, Oleg Palygin, Rajen B Mistry, Colin McKenzie, Andrew Macdonald, Gyorgy Hutvagner, J Simon C Arthur, Bruno G Frenguelli, Yuriy Pankratov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637221?pdf=render