Anti-hyperalgesic effects of photobiomodulation therapy (904 nm) on streptozotocin-induced diabetic neuropathy imply MAPK pathway and calcium dynamics modulation

Anti-hyperalgesic effects of photobiomodulation therapy (904 nm) on streptozotocin-induced diabetic neuropathy imply MAPK pathway and calcium dynamics modulation

Abstract Several recent studies have established the efficacy of photobiomodulation therapy (PBMT) in painful clinical conditions. Diabetic neuropathy (DN) can be related to activating mitogen-activated protein kinases (MAPK), such as p38, in the peripheral nerve. MAPK pathway is activated in respon...

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Bibliographic Details
Main Authors: Willians Fernando Vieira, Kauê Franco Malange, Silviane Fernandes de Magalhães, Júlia Borges Paes Lemes, Gilson Gonçalves dos Santos, Catarine Massucato Nishijima, Alexandre Leite Rodrigues de Oliveira, Maria Alice da Cruz-Höfling, Cláudia Herrera Tambeli, Carlos Amilcar Parada
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19947-2

Internet

https://doi.org/10.1038/s41598-022-19947-2

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