Histone Deacetylases and Their Potential as Targets to Enhance Tumour Radiosensitisation
In mammalian cells, genomic DNA is packaged with histone proteins and condensed into chromatin. To gain access to the DNA, chromatin remodelling is required that is enhanced through histone post-translational modifications, which subsequently stimulate processes including DNA repair and transcriptio...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
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Series: | Radiation |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-592X/2/1/11 |