Histone Deacetylases and Their Potential as Targets to Enhance Tumour Radiosensitisation

In mammalian cells, genomic DNA is packaged with histone proteins and condensed into chromatin. To gain access to the DNA, chromatin remodelling is required that is enhanced through histone post-translational modifications, which subsequently stimulate processes including DNA repair and transcriptio...

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Bibliographic Details
Main Authors: Jennifer Antrobus, Jason L. Parsons
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Radiation
Subjects:
Online Access:https://www.mdpi.com/2673-592X/2/1/11