Cell Uptake of Steroid-BODIPY Conjugates and Their Internalization Mechanisms: Cancer Theranostic Dyes

Cell Uptake of Steroid-BODIPY Conjugates and Their Internalization Mechanisms: Cancer Theranostic Dyes

Estradiol-BODIPY linked via an 8-carbon spacer chain and 19-nortestosterone- and testosterone-BODIPY linked via an ethynyl spacer group were evaluated for cell uptake in the breast cancer cell lines MCF-7 and MDA-MB-231 and prostate cancer cell lines PC-3 and LNCaP, as well as in normal dermal fibro...

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Bibliographic Details
Main Authors: Ana F. Amendoeira, André Luz, Ruben Valente, Catarina Roma-Rodrigues, Hasrat Ali, Johan E. van Lier, Fernanda Marques, Pedro V. Baptista, Alexandra R. Fernandes
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
estradiol-BODIPY conjugates
androgen-BODIPY conjugates
fluorescence imaging
photosensitizers
receptor-mediated cell uptake
photodynamic therapy
Online Access:https://www.mdpi.com/1422-0067/24/4/3600

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https://www.mdpi.com/1422-0067/24/4/3600

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