The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism

The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism

Sulforaphane (SFN), an isothiocyanate present in cruciferous vegetables such as broccoli and brussels sprouts, has a variety of biological functions. This study was undertaken to assess the potential efficacy of SFN in ameliorating dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) in mice...

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Bibliographic Details
Main Authors: Canxia He, Mingfei Gao, Xiaohong Zhang, Peng Lei, Haitao Yang, Yanping Qing, Lina Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Nutrition
Subjects:
sulforaphane
ulcerative colitis
gut microbiota
Nrf2
inflammation
intestinal barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.893344/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.893344/full

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