Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain

Abstract In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules and are consequently involved in disease progression. We have investigated the proteomic profiles of EVs that were isolated from four different human‐induced pluripotent stem cell‐derived neural cell t...

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Bibliographic Details
Main Authors: Yang You, Satoshi Muraoka, Mark P. Jedrychowski, Jianqiao Hu, Amanda K. McQuade, Tracy Young‐Pearse, Roshanak Aslebagh, Scott A. Shaffer, Steven P. Gygi, Mathew Blurton‐Jones, Wayne W. Poon, Tsuneya Ikezu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Extracellular Vesicles
Online Access:https://doi.org/10.1002/jev2.12183