3D-Organotypic Cultures to Unravel Molecular and Cellular Abnormalities in Atopic Dermatitis and Ichthyosis Vulgaris

3D-Organotypic Cultures to Unravel Molecular and Cellular Abnormalities in Atopic Dermatitis and Ichthyosis Vulgaris

Atopic dermatitis (AD) is characterized by dry and itchy skin evolving into disseminated skin lesions. AD is believed to result from a primary acquired or a genetically-induced epidermal barrier defect leading to immune hyper-responsiveness. Filaggrin (FLG) is a protein found in the cornified envelo...

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Bibliographic Details
Main Authors: Géraldine Leman, Verena Moosbrugger-Martinz, Stefan Blunder, Petra Pavel, Sandrine Dubrac
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
atopic dermatitis
ichthyosis
organotypic culture
epidermal equivalent
skin equivalent
filaggrin
Online Access:https://www.mdpi.com/2073-4409/8/5/489

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https://www.mdpi.com/2073-4409/8/5/489

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