LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration

Lymphoid progenitors migrate from the bone marrow into the thymus to give rise to T and NK cell lineages. Here the authors characterize a lymphotoxin receptor beta-dependent population of thymic endothelial cells that guide lymphoid progenitor homing in the thymus.

Bibliographic Details
Main Authors: Yaoyao Shi, Weiwei Wu, Qian Chai, Qingqing Li, Yu Hou, Huan Xia, Boyang Ren, Hairong Xu, Xiaohuan Guo, Caiwei Jin, Mengjie Lv, Zhongnan Wang, Yang-Xin Fu, Mingzhao Zhu
Format: Article
Language:English
Published: Nature Portfolio 2016-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12369