Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes

Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes

Smad transcription factors are the main downstream effectors of the Transforming growth factor β superfamily (TGFβ) signalling network. The DNA complexes determined here by X-ray crystallography for the Bone Morphogenetic Proteins (BMP) activated Smad5 and Smad8 proteins reveal that all MH1 domains...

Full description

Bibliographic Details
Main Authors: Lidia Ruiz, Zuzanna Kaczmarska, Tiago Gomes, Eric Aragon, Carles Torner, Regina Freier, Blazej Baginski, Pau Martin-Malpartida, Natàlia de Martin Garrido, José. A. Marquez, Tiago N. Cordeiro, Radoslaw Pluta, Maria J. Macias
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Smad
Transcription factor
Protein-DNA
MH1 domain
BMP signaling
Smad5
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021000027

Internet

http://www.sciencedirect.com/science/article/pii/S2001037021000027

Similar Items