PEG minocycline-liposomes ameliorate CNS autoimmune disease.

PEG minocycline-liposomes ameliorate CNS autoimmune disease.

Minocycline is an oral tetracycline derivative with good bioavailability in the central nervous system (CNS). Minocycline, a potent inhibitor of matrix metalloproteinase (MMP)-9, attenuates disease activity in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS...

Full description

Bibliographic Details
Main Authors: Wei Hu, Josbert Metselaar, Li-Hong Ben, Petra D Cravens, Mahendra P Singh, Elliot M Frohman, Todd N Eagar, Michael K Racke, Bernd C Kieseier, Olaf Stüve
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2613526?pdf=render

Internet

http://europepmc.org/articles/PMC2613526?pdf=render

Similar Items