Newly developed controlled release subcutaneous formulation for tramadol hydrochloride

This study presents a drug delivery system of poly (Ɛ-caprolactone) (PCL) ribbons to optimize the pharmaceutical action of tramadol for the first time according to our knowledge. PCL ribbons were fabricated and loaded with tramadol HCl. Ribbons were prepared by slip casting technique and coated with...

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Bibliographic Details
Main Authors: Mostafa Mabrouk, Hanan H. Beherei, Shaimaa ElShebiney, Masaru Tanaka
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016418300148