Amorphous Solid Dispersions (ASDs): The Influence of Material Properties, Manufacturing Processes and Analytical Technologies in Drug Product Development

Amorphous Solid Dispersions (ASDs): The Influence of Material Properties, Manufacturing Processes and Analytical Technologies in Drug Product Development

Poorly water-soluble drugs pose a significant challenge to developability due to poor oral absorption leading to poor bioavailability. Several approaches exist that improve the oral absorption of such compounds by enhancing the aqueous solubility and/or dissolution rate of the drug. These include ch...

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Bibliographic Details
Main Authors: Raman Iyer, Vesna Petrovska Jovanovska, Katja Berginc, Miha Jaklič, Flavio Fabiani, Cornelius Harlacher, Tilen Huzjak, Manuel Vicente Sanchez-Felix
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceutics
Subjects:
amorphous solid dispersions
characterization
manufacturing processes
novel stabilizing polymers
material properties
Online Access:https://www.mdpi.com/1999-4923/13/10/1682

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https://www.mdpi.com/1999-4923/13/10/1682

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