498 Bruton’s tyrosine kinase (BTK) inhibitors impede platelet aggregation but not adhesion to collagen.

OBJECTIVES/GOALS: The research objectives of this project are to elucidate the effects of Bruton’s tyrosine kinase inhibitors (BTKi) of varying target specificity on platelet function with regard to platelet aggregation, adhesion, spreading, and intracellular signaling as measured by kinase phosphor...

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Bibliographic Details
Main Authors: Thomas Kartika, Lorena Buitrago, Jihong Li, Barry S. Coller
Format: Article
Language:English
Published: Cambridge University Press 2024-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124004229/type/journal_article