Identification of lncRNA–miRNA–mRNA Networks Linked to Non-small Lung Cancer Resistance to Inhibitors of Epidermal Growth Factor Receptor

Identification of lncRNA–miRNA–mRNA Networks Linked to Non-small Lung Cancer Resistance to Inhibitors of Epidermal Growth Factor Receptor

Background: Tyrosine kinase inhibitors that act against epidermal growth factor receptor (EGFR) show strong efficacy against non-small cell lung cancer (NSCLC) involving mutated EGFRs. However, most such patients eventually develop resistance to EGFR-TKIs. Numerous researches have reported that mess...

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Bibliographic Details
Main Authors: Ting Wang, Chengliang Yang, Bing Li, Ying Xing, Jian Huang, Yangping Zhang, Shanshan Bu, Hong Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
EGFR-TKI
resistance
NSCLC
competitive endogenous RNA
network
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.758591/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.758591/full

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