iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis

iTRAQ-Based Proteomic Analysis of Dentate Gyrus in Temporal Lobe Epilepsy With Hippocampal Sclerosis

Temporal lobe epilepsy (TLE) is the most frequent type of focal epilepsy in adults, typically resistant to pharmacological treatment, and mostly presents with cognitive impairment and psychiatric comorbidities. The most common neuropathological hallmark in TLE patients is hippocampal sclerosis (HS)....

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Bibliographic Details
Main Authors: Wenbiao Xiao, Zhiquan Yang, Xiaoxin Yan, Li Feng, Lili Long, Tian Tu, Na Deng, Wenjuan Chen, Bo Xiao, Hongyu Long, Yi Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neurology
Subjects:
temporal lobe epilepsy
hippocampal sclerosis
dentate gyrus
quantitative proteomics
iTRAQ
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.626013/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2020.626013/full

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