Adaptive evolution of proteins in hepatitis B virus during divergence of genotypes

Abstract Hepatitis B virus (HBV) is classified into several genotypes, correlated with different geographic distributions, clinical outcomes and susceptible human populations. It is crucial to investigate the evolutionary significance behind the diversification of HBV genotypes, because it improves...

Full description

Bibliographic Details
Main Authors: Shengdi Li, Zhen Wang, Yixue Li, Guohui Ding
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02012-8