Research advances in the therapeutic potential of xanthine oxidoreductase inhibitors for periodontitis

Research advances in the therapeutic potential of xanthine oxidoreductase inhibitors for periodontitis

Periodontitis is associated with abnormal purine metabolism, which is manifested by increased uric acid in host blood and increased expression of the purine-degrading enzyme, xanthine oxidoreductase (XOR), in periodontal tissues. Both XOR and uric acid are pro-oxidative and pro-inflammatory mediator...

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Bibliographic Details
Main Authors: LI Yongshan, WU Zhicong, WANG Zixing, YU Xihuang, LIU Xi, YU Ting
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2023-12-01
Series:口腔疾病防治
Subjects:
periodontitis
host immune modulation
purine catabolism
urate-lowering drugs
xanthine oxidoreductase inhibitors
febuxostat
allopurinol
inflammation
oxidative stress
Online Access:https://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.12.010

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https://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2023.12.010

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