Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer’s pathology

Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer’s pathology

Summary: A prevailing hypothesis is that neurofibrillary tangles play a causal role in driving cognitive decline in Alzheimer’s disease (AD) because tangles correlate anatomically with areas that undergo neuronal loss. We used two-photon longitudinal imaging to directly test this hypothesis and obse...

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Bibliographic Details
Main Authors: Theodore J. Zwang, Eric del Sastre, Nina Wolf, Nancy Ruiz-Uribe, Benjamin Woost, Zachary Hoglund, Zhanyun Fan, Joshua Bailey, Lois Nfor, Luc Buée, K. Peter R. Nilsson, Bradley T. Hyman, Rachel E. Bennett
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724009033

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http://www.sciencedirect.com/science/article/pii/S2211124724009033

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