Inhibitory Effect of 1,8-Cineol on β-Catenin Regulation, WNT11 Expression, and Cellular Progression in HNSCC

Inhibitory Effect of 1,8-Cineol on β-Catenin Regulation, WNT11 Expression, and Cellular Progression in HNSCC

ObjectivesHead and neck squamous cell carcinoma (HNSCC) is one of the most common tumors worldwide. The high mortality rates have not changed during the last three decades, and thus there is an enormous need for innovative therapy approaches. Several recent studies suggest an important role of the W...

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Bibliographic Details
Main Authors: Anna Roettger, Karl-Ludwig Bruchhage, Maren Drenckhan, Kirsten Ploetze-Martin, Ralph Pries, Barbara Wollenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Oncology
Subjects:
HNSCC
1,8-cineol
WNT
β-catenin
WNT11
glycogen synthase kinase 3
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00092/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00092/full

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