Stimulation of the farnesoid X receptor promotes M2 macrophage polarization

Stimulation of the farnesoid X receptor promotes M2 macrophage polarization

FXR is a key molecule that modulates anti-inflammatory activity in the intestinal-liver axis. Although FXR has pleiotropic functions including regulation of liver inflammation and activation of macrophages, it remains unclear whether it is involved in macrophage polarization. In this paper we demons...

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Bibliographic Details
Main Authors: Thiranut Jaroonwitchawan, Hideki Arimochi, Yuki Sasaki, Chieko Ishifune, Hiroyuki Kondo, Kunihiro Otsuka, Shin-ichi Tsukumo, Koji Yasutomo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
farnesoid X receptor
macrophage
cell differentiation
inflammation
tissue repair
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1065790/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1065790/full

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