The matricellular receptor LRP1 forms an interface for signaling and endocytosis in modulation of the extracellular tumor environment

The membrane protein low-density lipoprotein receptor related-protein 1 (LRP1) has been attributed a role in cancer. However, its presumably often indirect involvement is far from understood. LRP1 has both endocytic and signaling activities. As a matricellular receptor it is involved in regulation,...

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Bibliographic Details
Main Authors: Bart eVan Gool, Stéphane eDedieu, Hervé eEmonard, Anton eRoebroek
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00271/full