Can harmful lifestyle, obesity and weight changes increase the risk of breast cancer in BRCA 1 and BRCA 2 mutation carriers? A Mini review

Abstract Background and aim The BRCA 1 and BRCA 2 genes are associated with an inherited susceptibility to breast cancer with a cumulative risk of 60% in BRCA 1 mutation carriers and of 30% in BRCA 2 mutation carriers. Several lifestyle factors could play a role in determining an individual’s risk o...

Full description

Bibliographic Details
Main Authors: A. Daniele, R. Divella, B. Pilato, S. Tommasi, P. Pasanisi, M. Patruno, M. Digennaro, C. Minoia, M. Dellino, S. Pisconti, P. Casamassima, E. Savino, A. V. Paradiso
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13053-021-00199-6