Vincamine Modulates the Effect of Pantoprazole in Renal Ischemia/Reperfusion Injury by Attenuating MAPK and Apoptosis Signaling Pathways

Vincamine Modulates the Effect of Pantoprazole in Renal Ischemia/Reperfusion Injury by Attenuating MAPK and Apoptosis Signaling Pathways

Pantoprazole has an antioxidant function against reactive oxygen species (ROS). Vincamine, a herbal candidate, is an indole alkaloid of clinical use against brain sclerosis. The aim of the present experiment is to evaluate, on a molecular level for the first time, the value of vincamine in addition...

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Bibliographic Details
Main Authors: Michael A. Fawzy, Sherif A. Maher, Mahmoud A. El-Rehany, Nermeen N. Welson, Nisreen K. A. Albezrah, Gaber El-Saber Batiha, Moustafa Fathy
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
vincamine
pantoprazole
renal ischemia/reperfusion injury
ROS
MAPK
apoptosis
Online Access:https://www.mdpi.com/1420-3049/27/4/1383

Internet

https://www.mdpi.com/1420-3049/27/4/1383

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