Survival and Integration of Neurons Derived from Human Embryonic Stem Cells in MPTP-Lesioned Primates

A human embryonic stem cell (HESC) line, H1, was studied after differentiation to a dopaminergic phenotype in vitro in order to carry out in vivo studies in Parkinsonian monkeys. To identify morphological characteristics of transplanted donor cells, HESCs were transfected with a GFP lentiviral vecto...

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Bibliographic Details
Main Authors: Dustin R. Wakeman, Stephanie Weiss, John R. Sladek, John D. Elsworth, Brian Bauereis, Csaba Leranth, Patrick J. Hurley, Robert H. Roth, D. Eugene Redmond
Format: Article
Language:English
Published: SAGE Publishing 2014-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368913X664865