Modulation of the Cellular Microenvironment by Mechanical Fluid Shear Stress and Hypoxia Alters the Differentiation Capacity of Skeletal Muscle-Derived Stem Cells

Modulation of the Cellular Microenvironment by Mechanical Fluid Shear Stress and Hypoxia Alters the Differentiation Capacity of Skeletal Muscle-Derived Stem Cells

Skeletal muscle-derived stem cells (MDSCs) are the key modulators of muscle regeneration. An inappropriate cellular microenvironment can reduce the regenerative capacity of MDSCs. This study evaluates the effect of microenvironmental alterations on the cell differentiation capacity using either mech...

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Bibliographic Details
Main Authors: Paula Hawlitschek, Michele C. Klymiuk, Asmaa Eldaey, Sabine Wenisch, Stefan Arnhold, Mohamed I. Elashry
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Applied Sciences
Subjects:
skeletal muscle
stem cells
fluid shear stress
hypoxia
myogenic differentiation
Online Access:https://www.mdpi.com/2076-3417/14/7/3047

Internet

https://www.mdpi.com/2076-3417/14/7/3047

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