Quantitative proteomics of small numbers of closely-related cells: Selection of the optimal method for a clinical setting

Quantitative proteomics of small numbers of closely-related cells: Selection of the optimal method for a clinical setting

Mass spectrometry (MS)-based proteomics profiling has undoubtedly increased the knowledge about cellular processes and functions. However, its applicability for paucicellular sample analyses is currently limited. Although new approaches have been developed for single-cell studies, most of them have...

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Main Authors: Kyra van der Pan, Sara Kassem, Indu Khatri, Arnoud H. de Ru, George M. C. Janssen, Rayman T. N. Tjokrodirijo, Fadi al Makindji, Eftychia Stavrakaki, Anniek L. de Jager, Brigitta A. E. Naber, Inge F. de Laat, Alesha Louis, Wouter B. L. van den Bossche, Lisette B. Vogelezang, Rutger K. Balvers, Martine L. M. Lamfers, Peter A. van Veelen, Alberto Orfao, Jacques J. M. van Dongen, Cristina Teodosio, Paula Díez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
proteome characterization
low cell numbers
closely-related cells
monocyte
macrophage
paucicellular clinical samples
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.997305/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.997305/full

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