A Standardized Collagen-Based Scaffold Improves Human Hepatocyte Shipment and Allows Metabolic Studies over 10 Days

Due to pronounced species differences, hepatotoxicity of new drugs often cannot be detected in animal studies. Alternatively, human hepatocytes could be used, but there are some limitations. The cells are not always available on demand or in sufficient amounts, so far there has been only limited suc...

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Bibliographic Details
Main Authors: Marc Ruoß, Victor Häussling, Frank Schügner, Leon H. H. Olde Damink, Serene M. L. Lee, Liming Ge, Sabrina Ehnert, Andreas K. Nussler
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Bioengineering
Subjects:
Online Access:http://www.mdpi.com/2306-5354/5/4/86