Insights into the Peritumoural Brain Zone of Glioblastoma: <i>CDK4</i> and <i>EXT2</i> May Be Potential Drivers of Malignancy

Insights into the Peritumoural Brain Zone of Glioblastoma: <i>CDK4</i> and <i>EXT2</i> May Be Potential Drivers of Malignancy

Despite the efforts made in recent decades, glioblastoma is still the deadliest primary brain cancer without cure. The potential role in tumour maintenance and progression of the peritumoural brain zone (PBZ), the apparently normal area surrounding the tumour, has emerged. Little is known about this...

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Bibliographic Details
Main Authors: Martina Giambra, Andrea Di Cristofori, Donatella Conconi, Matilde Marzorati, Serena Redaelli, Melissa Zambuto, Alessandra Rocca, Louis Roumy, Giorgio Carrabba, Marialuisa Lavitrano, Gaia Roversi, Carlo Giussani, Angela Bentivegna
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
peritumoural brain zone
<i>CDK4</i>
<i>EXT2</i>
malignant transformation
Online Access:https://www.mdpi.com/1422-0067/24/3/2835

Internet

https://www.mdpi.com/1422-0067/24/3/2835

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