Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1

Summary: Neurodegeneration is a process involving both cell autonomous and non-cell autonomous neuron loss, followed by a collapse of neural networks, but its pathogenesis is poorly understood. We have previously demonstrated that Eomes-positive helper T (Eomes + Th) cells recognizing LINE-1(L1)-der...

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Bibliographic Details
Main Authors: Fumio Takahashi, Chenyang Zhang, Hirohiko Hohjoh, Ben Raveney, Takashi Yamamura, Nobuhiro Hayashi, Shinji Oki
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422200548X