Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells
Objective(s): Frizzled-7, the most common receptor of the Wnt signaling pathway, was significantly over-expressed in gastric (GC) and colorectal (CRC) cancers and stimulated tumorigenesis. The extracellular domain of Fzd7 (sFzd7) as a decoy receptor, could competitively bound with ligands and antago...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2022-02-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://ijbms.mums.ac.ir/article_19608_c1d94b0754f52f6e2119a18b16e9eb98.pdf |