Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells

Objective(s): Frizzled-7, the most common receptor of the Wnt signaling pathway, was significantly over-expressed in gastric (GC) and colorectal (CRC) cancers and stimulated tumorigenesis. The extracellular domain of Fzd7 (sFzd7) as a decoy receptor, could competitively bound with ligands and antago...

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Bibliographic Details
Main Authors: Nasim Hafezi, Reza Valadan, Hossein Asgarian-Omran, Abolghasem Ajami
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_19608_c1d94b0754f52f6e2119a18b16e9eb98.pdf