Anti-tumor activity of a recombinant soluble Fzd7 decoy receptor in human gastric and colon cancer cells
Objective(s): Frizzled-7, the most common receptor of the Wnt signaling pathway, was significantly over-expressed in gastric (GC) and colorectal (CRC) cancers and stimulated tumorigenesis. The extracellular domain of Fzd7 (sFzd7) as a decoy receptor, could competitively bound with ligands and antago...
Main Authors: | Nasim Hafezi, Reza Valadan, Hossein Asgarian-Omran, Abolghasem Ajami |
---|---|
Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2022-02-01
|
Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | https://ijbms.mums.ac.ir/article_19608_c1d94b0754f52f6e2119a18b16e9eb98.pdf |
Similar Items
-
FZD5 prevents epithelial-mesenchymal transition in gastric cancer
by: Dan Dong, et al.
Published: (2021-02-01) -
Targeting Wnt Signaling for the Treatment of Gastric Cancer
by: Sarah Koushyar, et al.
Published: (2020-05-01) -
FZD10 Carried by Exosomes Sustains Cancer Cell Proliferation
by: Maria Principia Scavo, et al.
Published: (2019-07-01) -
LncRNA FGD5-AS1 drives the malignant development of gastric cancer by negatively interacting with FZD3
by: Limin Feng, et al.
Published: (2022-06-01) -
Exosome Released FZD10 Increases Ki-67 Expression via Phospho-ERK1/2 in Colorectal and Gastric Cancer
by: Maria Principia Scavo, et al.
Published: (2021-09-01)