Characterization of pain-, anxiety-, and cognition-related behaviors in the complete Freund's adjuvant model of chronic inflammatory pain in Wistar–Kyoto rats

Characterization of pain-, anxiety-, and cognition-related behaviors in the complete Freund's adjuvant model of chronic inflammatory pain in Wistar–Kyoto rats

IntroductionChronic pain is often associated with comorbid anxiety and cognitive dysfunction, negatively affecting therapeutic outcomes. The influence of genetic background on such interactions is poorly understood. The stress-hyperresponsive Wistar–Kyoto (WKY) rat strain, which models aspects of an...

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Bibliographic Details
Main Authors: Mehnaz I. Ferdousi, Patricia Calcagno, Connie Sanchez, Karen L. Smith, John P. Kelly, Michelle Roche, David P. Finn
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pain Research
Subjects:
chronic pain
stress
anxiety
cognition
complete Freund's adjuvant
Wistar–Kyoto rats
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2023.1131069/full

Internet

https://www.frontiersin.org/articles/10.3389/fpain.2023.1131069/full

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