Post-translational changes in Phialophora verrucosa via lysine lactylation during prolonged presence in a patient with a CARD9-related immune disorder

Post-translational changes in Phialophora verrucosa via lysine lactylation during prolonged presence in a patient with a CARD9-related immune disorder

CARD9-related inherited immune disorders are a major risk factor for chronic disseminated fungal infection. In addition to pathogens of Candida and dermatophytes, the environmental opportunists of the black yeast-like fungi are relatively frequent in this patient cohort. Particularly the genus Phial...

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Bibliographic Details
Main Authors: Yinggai Song, Xiao Liu, J. Benjamin Stielow, Sybren de Hoog, Ruoyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
Post-translational modification
lysine lactylation
CARD9
micro-evolution
melanin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.966457/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.966457/full

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