CRISPR/Cas9 as tool for functional study of genes involved in preimplantation embryo development.

The CRISPR/Cas9 system has proven to be an efficient gene-editing tool for genome modification of cells and organisms. However, the applicability and efficiency of this system in pig embryos have not been studied in depth. Here, we aimed to remove porcine OCT4 function as a model case using the CRIS...

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Bibliographic Details
Main Authors: Jeongwoo Kwon, Suk Namgoong, Nam-Hyung Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4361403?pdf=render