Genomic Identification of the TOR Signaling Pathway as a Target of the Plant Alkaloid Antofine in the Phytopathogen <named-content content-type="genus-species">Fusarium graminearum</named-content>

Genomic Identification of the TOR Signaling Pathway as a Target of the Plant Alkaloid Antofine in the Phytopathogen <named-content content-type="genus-species">Fusarium graminearum</named-content>

ABSTRACT Antofine, a phenanthroindolizidine alkaloid, is a bioactive natural product isolated from milkweeds that exhibits numerous biological activities, including anticancer, antimicrobial, antiviral, and anti-inflammatory properties. However, the direct targets and mode of action of antofine have...

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Bibliographic Details
Main Authors: Christopher Mogg, Christopher Bonner, Li Wang, Johann Schernthaner, Myron Smith, Darrell Desveaux, Rajagopal Subramaniam
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mBio
Subjects:
Fusarium
drug targets
rapamycin
Online Access:https://journals.asm.org/doi/10.1128/mBio.00792-19

Internet

https://journals.asm.org/doi/10.1128/mBio.00792-19

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