Exploiting Broad-Spectrum Chimeric Lysin to Cooperate with Mupirocin against Staphylococcus aureus-Induced Skin Infections and Delay the Development of Mupirocin Resistance

Exploiting Broad-Spectrum Chimeric Lysin to Cooperate with Mupirocin against Staphylococcus aureus-Induced Skin Infections and Delay the Development of Mupirocin Resistance

ABSTRACT Staphylococcus aureus often leads to severe skin infections. However, S. aureus is facing a crisis of antibiotic resistance. The combination of phage and antibiotics is effective for drug-resistant S. aureus infections. Therefore, it is worth exploiting novel antibacterial agents to coopera...

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Bibliographic Details
Main Authors: Xiao-chao Duan, Xin-xin Li, Xiang-min Li, Shuang Wang, Fen-qiang Zhang, Ping Qian
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
chimeric phage lysin
mupirocin
S. aureus infections
antibiotic resistance
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05050-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05050-22

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