Predicting cell population-specific gene expression from genomic sequence

Most regulatory elements, especially enhancer sequences, are cell population-specific. One could even argue that a distinct set of regulatory elements is what defines a cell population. However, discovering which non-coding regions of the DNA are essential in which context, and as a result, which ge...

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Bibliographic Details
Main Authors: Lieke Michielsen, Marcel J. T. Reinders, Ahmed Mahfouz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Bioinformatics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2024.1347276/full