Hsa_circ_0004831 downregulation is partially responsible for atorvastatinalleviated human umbilical vein endothelial cell injuries induced by ox-LDL through targeting the miR-182-5p/CXCL12 axis

Abstract Background The dysfunction and injury of human umbilical vein endothelial cells (HUVECs) are key events of atherosclerosis (AS). Atorvastatin (ATV) has been shown to play a protective role on endothelial cells. However, the associated molecular mechanisms remain not fully illustrated. Metho...

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Bibliographic Details
Main Authors: Gang Su, Guangli Sun, Jian Lv, Weiwei Zhang, Hai Liu, Yajing Tang, Haoang Su
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-021-01998-4