Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors
A new type of berberine derivatives was obtained by the reaction of berberrubine with aliphatic sulfonyl chlorides. The new polycyclic compounds have a sultone ring condensed to <i>C</i> and <i>D</i> rings of a protoberberine core. The reaction conditions were developed to fa...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/7/1945 |