The mechanism of colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment

The mechanism of colon tissue damage mediated by HIF-1α/NF-κB/STAT1 in high-altitude environment

The high-altitude environment damages the intestinal mucosal barrier, leading to a high incidence of intestinal diseases and seriously affects the working ability of people at high altitude. However, how high altitude induces intestinal mucosal barrier injury has not been well defined. The purpose o...

Full description

Bibliographic Details
Main Authors: Junfei Cheng, Yuemei Sun, Jiaxin He, Zihan Wang, Wenbin Li, Rong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Physiology
Subjects:
high altitude
colon
inflammation
hypoxia inducible factor-1α (HIF-1α)
STAT1
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.933659/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.933659/full

Similar Items