Evaluations of candidate markers of dihydroartemisinin-piperaquine resistance in Plasmodium falciparum isolates from the China–Myanmar, Thailand–Myanmar, and Thailand–Cambodia borders

Abstract Background The fast-declining clinical efficacy of dihydroartemisinin-piperaquine (DHA-PPQ) in Cambodia is a warning of the underlying westward dissemination of piperaquine resistance in the Greater Mekong Subregion (GMS). Mutations in the Plasmodium falciparum Kelch 13-propeller (PfK13) an...

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Bibliographic Details
Main Authors: Run Ye, Yilong Zhang, Dongmei Zhang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Parasites & Vectors
Subjects:
Online Access:https://doi.org/10.1186/s13071-022-05239-1