Contractility analysis of human engineered 3D heart tissues by an automatic tracking technique using a standalone application.

The use of Engineered Heart Tissues (EHT) as in vitro model for disease modeling and drug screening has increased, as they provide important insight into the genetic mechanisms, cardiac toxicity or drug responses. Consequently, this has highlighted the need for a standardized, unbiased, robust and a...

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Bibliographic Details
Main Authors: José M Rivera-Arbeláez, Carla Cofiño-Fabres, Verena Schwach, Tom Boonen, Simone A Ten Den, Kim Vermeul, Albert van den Berg, Loes I Segerink, Marcelo C Ribeiro, Robert Passier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0266834