Synthesis of Carrier-Free Paclitaxel–Curcumin Nanoparticles: The Role of Curcuminoids

Synthesis of Carrier-Free Paclitaxel–Curcumin Nanoparticles: The Role of Curcuminoids

The systemic administration of paclitaxel (PTX)-based combinatorial therapies is significantly restricted due to the multidrug resistance. Curcumin (CUR) not only inhibits cancer-cell proliferation but also reverses the PTX resistance. However, achieving codelivery of these two drugs is a challenge...

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Bibliographic Details
Main Authors: Sena Karaosmanoglu, Yunsen Zhang, Wenli Zhou, Defang Ouyang, Xianfeng Chen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Bioengineering
Subjects:
hydrophobic anticancer drugs
curcumin
paclitaxel
carrier-free nanoparticles
self-assembly
molecular modeling
Online Access:https://www.mdpi.com/2306-5354/9/12/815

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https://www.mdpi.com/2306-5354/9/12/815

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