Cooperation of loss of NKX3.1 and inflammation in prostate cancer initiation

Cooperation of loss of NKX3.1 and inflammation in prostate cancer initiation

Although it is known that inflammation plays a critical role in prostate tumorigenesis, the underlying processes are not well understood. Based on analysis of genetically engineered mouse models combined with correlative analysis of expression profiling data from human prostate tumors, we demonstrat...

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Bibliographic Details
Main Authors: Clémentine Le Magnen, Renu K. Virk, Aditya Dutta, Jaime Yeji Kim, Sukanya Panja, Zoila A. Lopez-Bujanda, Andrea Califano, Charles G. Drake, Antonina Mitrofanova, Cory Abate-Shen
Format: Article
Language:English
Published: The Company of Biologists 2018-11-01
Series:Disease Models & Mechanisms
Subjects:
Prostate cancer
Cancer initiation
NKX3.1
Inflammation
Differentiation
Online Access:http://dmm.biologists.org/content/11/11/dmm035139

Internet

http://dmm.biologists.org/content/11/11/dmm035139

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