Transient receptor potential vanilloid 1-expressing cardiac afferent nerves may contribute to cardiac hypertrophy in accompany with an increased expression of brain-derived neurotrophic factor within nucleus tractus solitarius in a pressure overload model

Transient receptor potential vanilloid 1-expressing cardiac afferent nerves may contribute to cardiac hypertrophy in accompany with an increased expression of brain-derived neurotrophic factor within nucleus tractus solitarius in a pressure overload model

Introduction Increased sympathetic output contributes to cardiac hypertrophy. Sympathoexcitation is induced by activating the cardiac sympathetic afferent nerves through transient receptor potential vanilloid 1 (TRPV1) in cardiac afferent endings. Brainstem nucleus tractus solitarius (NTS) receives...

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Bibliographic Details
Main Authors: Risa Shibata, Keisuke Shinohara, Shota Ikeda, Takeshi Iyonaga, Taku Matsuura, Soichiro Kashihara, Koji Ito, Takuya Kishi, Yoshitaka Hirooka, Hiroyuki Tsutsui
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Clinical and Experimental Hypertension
Subjects:
autonomic nervous system
cardiac hypertrophy
transient receptor potential vanilloid 1
brain-derived neurotrophic factor
brain
Online Access:http://dx.doi.org/10.1080/10641963.2022.2029470

Internet

http://dx.doi.org/10.1080/10641963.2022.2029470

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