Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Abstract Background Drosophila melanogaster has one of best-described transcriptomes of any multicellular organism. Nevertheless, the paucity of 3′-sequencing data in this species precludes comprehensive assessment of alternative polyadenylation (APA), which is subject to broad tissue-specific contr...

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Bibliographic Details
Main Authors: Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-017-1358-0