The role of myelin in Theiler's virus persistence in the central nervous system.
Theiler's virus, a picornavirus, persists for life in the central nervous system of mouse and causes a demyelinating disease that is a model for multiple sclerosis. The virus infects neurons first but persists in white matter glial cells, mainly oligodendrocytes and macrophages. The mechanism,...
| Hoofdauteurs: | , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Public Library of Science (PLoS)
2007-02-01
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| Reeks: | PLoS Pathogens |
| Online toegang: | http://europepmc.org/articles/PMC1797621?pdf=render |